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Fibroblast surface protein

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Published by New York Academy of Sciences in New York .
Written in English


  • Fibroblasts -- Congresses.,
  • Cell membranes -- Congresses.,
  • Glycoproteins -- Congresses.,
  • Fibroblasts -- Analysis -- Congresses.,
  • Membrane proteins -- Analysis -- Congresses.

Book details:

Edition Notes

Papers from a conference held by the New York Academy of Sciences, Nov. 30 and Dec. 1-2, 1977.

Statementedited by Antti Vaheri, Erkki Ruoslahti, and Deane F. Mosher.
SeriesAnnals of the New York Academy of Sciences ; v. 312, Annals of the New York Academy of Sciences ;, v. 312.
ContributionsVaheri, Antti., Ruoslahti, Erkki., Mosher, Deane F., New York Academy of Sciences.
LC ClassificationsQ11 .N5 vol. 312, QP88.23 .N5 vol. 312
The Physical Object
Pagination456 p. :
Number of Pages456
ID Numbers
Open LibraryOL4727983M
ISBN 100890720681
LC Control Number78015899

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The lung fibroblast surface proteins PDGFRα and CDCP1 as profibrotic mediators in pulmonary fibrosisˮ is my own work. I have only used the sources indicated and have not made unauthorized use of services of a third party. Where the work of others has been quoted or . Fibronectin, a plasma protein immunologically identical with a major surface protein of normal fibroblasts, was found to bind to collagen and gelatin. A solid phase enzyme immunoassay was used for the binding tests. Collagen, gelatin or various control proteins were adsorbed to a plastic by:   Fibroblast activation protein (Fap; or seprase) is a proline-specific serine protease with both dipeptidyl peptidase and endopeptidase (collagenase and gelatinase) activities (Goldstein et al., ; Rettig et al., ; Scanlan et al., ).Cited by: 1. adshelp[at] The ADS is operated by the Smithsonian Astrophysical Observatory under NASA Cooperative Agreement NNX16AC86A.

We employed antibodies specific for anti‐fibroblast, FAP, and FSP to examine the expression of those proteins on the surface of breast and prostate non‐cancer and cancer tissue‐derived fibroblast cell lines and primary fibroblasts as well as on the surface of several in vitro‐cultivated non‐cancer and cancer‐derived epithelial cell lines. To further prove the specificity of the antibodies, we examined . Fibroblast activation protein (FAP) is a cell surface-bound protease of the prolyl oligopeptidase gene family expressed at sites of tissue remodelling. This study aimed to delineate the expression of FAP in cirrhotic human liver and examine its biochemical activities. Anti-Fibroblast Surface Protein antibody [1B10] (ab) is not available Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June as it has been generated by the ascites method. I have tried using 'Anti-fibroblast surface marker protein' from Sigma but have had mixed results. Any other suggestions would be extremely helpful. Thank you very much in advance.

The identification of fibroblasts and cancer-associated fibroblasts from human cancer tissue using surface markers is difficult, especially because the markers used currently are usually not expressed solely by fibroblasts, and the identification of fibroblast-specific surface molecules is . Six different proteins are found to be reproducibly exposed on the cell surface of chicken embryo fibroblasts (CEF) by the criterion of lactoperoxidase-catalyzed iodination (,, ,, ,, ,, 87,, daltons). Kawano D.F., de Paula da Silva C.H.T., Taft C.A. () Design of Inhibitors of the Human Fibroblast Activation Protein α as a Strategy to Hinder Metastasis and Angiogenesis. In: La Porta F., Taft C. (eds) Emerging Research in Science and Engineering Based on Advanced Experimental and Computational Strategies. Engineering Materials.   Within 30 minutes, its fixation on S. mutans is visible by immunofluorescence (MAC in red, fibroblast surface protein in green). (C) MAC fixation increases after fibroblast stimulation with LTA and (D) significantly reduces the bacteria viability. Incubation of cells/bacteria with CD59 demonstrates the implication of MAC.